I am a critically acclaimed actress known for my transformative roles. I've portrayed both historical figures and complex characters dealing with modern issues. My career spans both film and television, and I've often worked with prestigious directors. I am also known for my activism. Who am I?

1. I won an Oscar for Best Actress for my portrayal of a British monarch.
2. I am known for my striking physical transformations for various roles, sometimes gaining or losing significant weight.
3. I've played a prominent role in a series where I play a detective in a small town.
4. I have been nominated for multiple Academy Awards.